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Contraindicated. CYP3A4 is responsible for the formation and elimination of cariprazine's Lively metabolites. The effect of CYP3A4 inducers on cariprazine publicity hasn't been evaluated and also the Web effect is unclear.pentobarbital will decrease the level or result of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Sig
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